See But, Politically, He'd Have To Reconsider

"The bottom line is that, whatever good Oprah may have done with her money, when it comes to medicine and science, she is a force for evil. Her intentions may be the best in the world, but that is only why she is the living embodiment of the cliche that the road to hell is paved with good intentions. That's especially true when that same road is also paved with no mental filter of critical thinking to keep out nonsense, and Oprah clearly has no mental filter when it comes to pseudoscience and quackery."

-- Orac, who none-the-less voted for The Evil One's hand-picked candidate, which ain't exactly smart nor showing any kind of Respectful Insolence.